ADVANCING THE SCIENCE OF BURN & WOUND CARE
Powered by our non-cytotoxic hypochlorous technology, Puracyn® Plus is changing the landscape of burn and wound care.
PURACYN® PLUS
WOUND IRRIGATION SOLUTION
- Non-cytotoxic, non-irritating
- pH balanced
- Irrigates the wound or burn without harming healthy tissue
- Available in spikeable configuration
WOUND IRRIGATION
CYTOTOXICITY COMPARISON
Topical antiseptics such as Dakin’s Solution, hydrogen peroxide, and acetic acid are cytotoxic at typical concentrations and may impede wound healing.1,2 On the other hand, the use of saline or tap water is inappropriate for wound bed preparation in the context of bioburden and biofilm.3
| WOUND IRRIGANT | RESULTS |
|---|---|
| Saline (0.9% NaCl, pH 5.0) | Pass |
| Hypochlorous Acid (0.024%) | Pass |
| Sodium Hypochlorite (Dakin’s) (0.25%) | Fail |
| Sodium Hypochlorite (Dakin’s) (0.5%) | Fail |
| Hydrogen Peroxide (3%) | Fail |
| Chlorhexidine Gluconate (0.02%) | Fail |
| Povidone Iodine (7.5%) | Fail |
ANTIMICROBIAL
EFFECTIVENESS TESTING
Puracyn Plus contains hypochlorous acid, a known antimicrobial, which serves as a preservative to inhibit the growth of microorganisms within in the solution.
| ORGANISMS | THEORETICAL INOCULUM CONCENTRATION PER mL OF TEST ARTICLE |
MICROBIAL,REDUCTION (15 SECONDS) |
|---|---|---|
| K. pneumoniae | 1.32 x 107 | >99.99999% (7+ log reduction) |
| E. faecalis | 4.10 x 107 | |
| S. aureus MRSA | 6.55 x 107 | |
| S. epidermidis | 5.80 x 107 | |
| A. baumannii | 8.50 x 107 | |
| S. aureus | 8.75 x 107 | |
| P. aeruginosa | 5.20 x 107 | |
| E. coli | 8.90 x 107 | |
| C. albicans | 2.30 x 107 |
- Thomas EL, Lehrer RI, Rest RF. Human Neutrophil antimicrobial activity. Rev Infect Dis 1988; 10 Suppl 2: S450-6.
- Wolcott RD, Kennedy JP, Dowd, SE. Regular debridement is the main tool for maintaining a healthy wound bed in most chronic wounds. J Wound Care. 2009; 18(2): 54-56.
- Wang L, Bassiri M, Najafi R, Najafi K. Hypochlorous acid as a potential wound care agent. Part I. Stabilized hypochlorous acid: A component of the inorganic armamentarium of innate immunity. Journal of Burns and Wounds. 2007; 6: 65-79.